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“Skyland Trail is a model of care for people with mental illness …its services are simply state of the art.”

Rosalynn Carter
Former First Lady
October 2003

Depression
Georgia's Premier Depression Treatment Facility


Depression covers an extremely wide spectrum of experience, from the almost universal experiences such as grief and bereavement to apparently inexplicable despondence and melancholy. Every year more than 18 million Americans suffer from some type of depressive illness. This includes major depression; bipolar disorder (often called manic depression); and dysthymia, a form of depression that is milder, but long lasting. Often overlooked, chronic irritability may also be a sign of depression.

Untreated major depression can seriously disrupt social relationships and work. The hopelessness and emotional pain that can accompany severe depression can seriously compromise a person’s ability to care for themselves and increase the risk of suicide.

However, depression is one of the most treatable of all medical illnesses, and treatment for depression really works. More than 80 percent of people with depression realize successful results with medication, psychosocial therapies, or both. The earlier treatment begins, the more effective it can be. Early treatment decreases the likelihood of recurrences, and the sooner treatment begins, the greater its probable effectiveness. Generally, treatment for major depression is sought about six months after symptoms are first experienced.

Symptoms
Depression affects people in different ways. Not everyone has the same symptoms. However, professional help should be sought if: any five of the following indications are present for more than two weeks; suicide is a serious concern; or symptoms interfere with daily activities.

  • Insomnia; sleeping too much; awakening in early morning; interrupted sleep
  • Fatigue or loss of energy
  • Irritability and restlessness
  • Reduced appetite and weight loss; or increased appetite and weight gain
  • Indifference to very important situations
  • Loss of interest or lack of pleasure in activities, including sex
  • Difficulty concentrating, remembering, or making decisions
  • Feelings of guilt and hopelessness; a sense of being worthless
  • Thoughts of death or suicide
  • Persistent physical symptoms that don't respond to treatment (such as chronic pain or digestive disorders)

Causes

  • Diathesis-stress Every disorder is best explained by a "diathesis-stress" model: genetic predisposition interacting with stress. Stress varies from biological processes (such as exposure to viruses) to psychosocial processes (such as loss of employment).
  • Chemical imbalances In people with depression, certain brain chemicals, called neurotransmitters, are typically present in incorrect amounts. Changes in these chemicals may cause or contribute to clinical depression.
  • Cognition People with negative thinking patterns are more likely to develop clinical depression. Typically, these are pessimistic individuals. They may have low self-esteem, worry to excess, or feel they have little control over their lives.
  • Medications Some medications, such as anti-hypertension medications can cause depression.
  • Genetics A family history of clinical depression increases the risk for developing the disease, although it can occur in people with no family history of the illness.
  • Situational factors Events ranging from divorce to the death of a loved one can contribute to clinical depression. Life situations and transitions, such as financial problems or moving to a new location, can also be contributing factors. It's normal to feel sad because of such events; however, sadness that continues over a long period of time may require professional help.

Epidemiological characteristics
While not actually causing depression, the following factors point to causes of the illness:

  • Gender Women are twice as likely as men to experience major depression, although it is still unclear why this is the case. The higher incidence among women may be related to hormonal changes and/or stress. Women suffering from abuse or poverty may also have an increased risk of major depression.
  • Co-occurrence Major depression is more likely to occur along with certain illnesses such as Alzheimer's disease, diabetes, cancer, heart disease, hormonal disorders, Parkinson's disease, and stroke. Depression can also co-occur with mental illnesses such as eating disorders and anxiety disorders. Depression can also co-occur with alcohol and/or substance abuse.

Treatment
Treatment for clinical depression varies with individuals, and may include antidepressant medication, psychotherapy, behavior modification, or a combination of these options. Support groups can also be helpful in overcoming the illness. As with any disorder, treatment success is enhanced by exercise, stress reduction, balanced nutrition, and proper sleep.

Medication
Severe instances of depression should be treated with medication that acts on the brain chemistry, affecting the chemical pathways associated with mood. Monoamine oxidase inhibitors (MAOIs) have been prescribed for some time. Newer types of antidepressants include selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs), as well as aminoketones.

Non-pharmacological Therapies
A variety of non-pharmacological therapies have been found to be effective in treating milder depressions and are used as important supplements to medication in major depressive disorder. These include the following:

  • Psychotherapy
    Less severe forms of depression can be treated effectively with psychotherapy. In some instances, the course of therapy can be as short as 10 to 20 weeks.
  • Cognitive/behavioral therapy
    Some individuals respond well to therapy that helps change negative thought patterns and behavior that may contribute to depression.
  • Interpersonal therapy
    Problematic personal relationships can cause or deepen depression. Interpersonal therapy can help a person relate more effectively with others and bring about a positive change in relationships.
  • Electroconvulsive therapy
    When medication is not a viable option, when medications are not effective, or in cases of debilitation or high risk of suicide, electroconvulsive therapy may be used to relieve symptoms of depression. This treatment is a safe and painless procedure that stimulates the brain with a brief, controlled series of electrical pulses.

 

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